12. Chaker-Margot M, Werten S, Scheffzek K, Maier T. Structural basis for Ras inactivation by Neurofibromin. Molecular Cell. 2022 Apr 7;82(7):1288-1296.e5.
11. Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S. Nucleolar maturation of the human small subunit processome. Science. 2021 Sep 10;373(6560):eabj5338.
10. Jia JJ, Lahr RM, Solgaard MT, Moraes BJ, Pointet R, Yang AD, Celucci G, Graber TE, Hoang HD, Niklaus MR, Pena IA, Hollensen AK, Smith EM, Chaker-Margot M, Anton L, Dajadian C, Livingstone M, Hearnden J, Wang XD, Yu Y, Maier T, Damgaard CK, Berman AJ, Alain T, Fonseca B. mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1. Nucleic Acid Res. 2021 Jan;gkaa1239. doi: 10.1093/nar/gkaa1239
9. Chaker-Margot M, Klinge S. Assembly and early maturation of large subunit precursors. RNA. 2019 Apr;25(4):465-471. doi: 10.1261/rna.069799.118.
8. Bolze A, Boisson B, Bosch B, Antipenko A, Bouaziz M, Sackstein P, Chaker-Margot M, …, Klinge S, Abel L, Casanova JL. Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8007-E8016. doi: 10.1073/pnas.1805437115.
7. Chaker-Margot M. Assembly of the small ribosomal subunit in yeast: mechanism and regulation. RNA. 2018 Jul;24(7):881-891. doi: 10.1261/rna.066985.118. Invited paper for the RNA Society/Scaringe Award 2017.
6. Sanghai ZA, Miller L, Molloy KR, Barandun J, Hunziker M, Chaker-Margot M, Wang J, Chait BT, Klinge S. Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature. 2018 Apr 5;556(7699):126-129. doi: 10.1038/nature26156
5. Barandun J*, Chaker-Margot M*, Hunziker M*, Molloy KR, Chait BT, Klinge S. The complete structure of the small subunit processome. Nat Struct Mol Biol. 2017 Nov;24(11):944-953. doi: 10.1038/nsmb.3472. *these authors contributed equally
4. Chaker-Margot M, Barandun J, Hunziker M, Klinge S. Architecture of the yeast small subunit processome. Science. 2017 Jan 13;355(6321). pii: eaal1880. doi: 10.1126/science.aal1880.
3. Hunziker M, Barandun J, Petfalski E, Tan D, Delan-Forino C, Molloy KR, Kim KH, Dunn-Davies H, Shi Y, Chaker-Margot M, Chait BT, Walz T, Tollervey D, Klinge S. UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly. Nat Commun. 2016 Jun 29;7:12090. doi: 10.1038/ncomms12090.
2. Chaker-Margot M, Hunziker M, Barandun J, Dill BD, Klinge S. Stage-specific assembly events of the 6 megadalton small subunit processome initiate eukaryotic ribosome assembly. Nat Struct Mol Biol. 2015 Nov;22(11):920-3. doi: 10.1038/nsmb.3111.
1. Mascle XC, Cappodaccia L, Bourdeau V, Tremblay-Belzile S, Chaker-Margot M. Lussier-Price M, Aubry M, Ferbeyre G, Omichinski JG. Structural and functional characterization of the phosphorylation dependent interaction between PML and SUMO1. Structure. 2015 Jan 6;23(1):126-38. doi: 10.1016/j.str.2014.10.015.
The Chaker-Margot Lab 